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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF4B All Species: 40
Human Site: S300 Identified Species: 58.67
UniProt: Q2VIQ3 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q2VIQ3 NP_001092763.1 1234 140035 S300 L T R L L Q D S L G G N S H T
Chimpanzee Pan troglodytes XP_518055 1227 139177 S300 L T R L L Q D S L G G N S H T
Rhesus Macaque Macaca mulatta XP_001084213 1234 139742 S300 L T R L L Q D S L G G N S H T
Dog Lupus familis XP_549061 1234 139874 S301 L T R L L Q D S L G G N S H T
Cat Felis silvestris
Mouse Mus musculus P33174 1231 139533 S301 L T R L L Q D S L G G N S H T
Rat Rattus norvegicus Q7M6Z5 1394 158861 S305 I T R L L K D S L G G S A K T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90640 1225 138905 S302 L T R L L Q D S L G G N S H T
Frog Xenopus laevis Q91784 1226 138905 S301 L T R L L Q D S L G G N S H T
Zebra Danio Brachydanio rerio Q58G59 1363 154819 S311 I T R I L K D S L G G N A K T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P46867 784 88189 G9 S A K S R R P G T G S S Q T P
Honey Bee Apis mellifera XP_395595 1064 123475 D283 T T Y V G Y R D S K L T R L L
Nematode Worm Caenorhab. elegans P46873 699 78760
Sea Urchin Strong. purpuratus P46872 699 78679
Poplar Tree Populus trichocarpa XP_002302432 1055 118553 N260 L E Q M R K L N P V F P G D S
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_200901 1294 145204 S324 L T R L L Q D S L G G N S K T
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 Q153 I R D L L A P Q N D N L P V H
Conservation
Percent
Protein Identity: 100 97.9 90.9 91 N.A. 83.6 26.4 N.A. N.A. 71.3 66.6 25.1 N.A. 27.2 36.8 25.6 27.4
Protein Similarity: 100 98.8 94 94.7 N.A. 90.3 47.2 N.A. N.A. 83.7 80.1 44.1 N.A. 41 55.8 38.5 38.4
P-Site Identity: 100 100 100 100 N.A. 100 66.6 N.A. N.A. 100 100 66.6 N.A. 6.6 6.6 0 0
P-Site Similarity: 100 100 100 100 N.A. 100 93.3 N.A. N.A. 100 100 93.3 N.A. 26.6 13.3 0 0
Percent
Protein Identity: 31.9 N.A. N.A. 30.6 N.A. 26.6
Protein Similarity: 50 N.A. N.A. 49.1 N.A. 44
P-Site Identity: 6.6 N.A. N.A. 93.3 N.A. 13.3
P-Site Similarity: 40 N.A. N.A. 93.3 N.A. 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 0 0 7 0 0 0 0 0 0 13 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 7 0 0 0 63 7 0 7 0 0 0 7 0 % D
% Glu: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % F
% Gly: 0 0 0 0 7 0 0 7 0 69 63 0 7 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 44 7 % H
% Ile: 19 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 7 0 0 19 0 0 0 7 0 0 0 19 0 % K
% Leu: 57 0 0 63 69 0 7 0 63 0 7 7 0 7 7 % L
% Met: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 7 7 0 7 57 0 0 0 % N
% Pro: 0 0 0 0 0 0 13 0 7 0 0 7 7 0 7 % P
% Gln: 0 0 7 0 0 50 0 7 0 0 0 0 7 0 0 % Q
% Arg: 0 7 63 0 13 7 7 0 0 0 0 0 7 0 0 % R
% Ser: 7 0 0 7 0 0 0 63 7 0 7 13 50 0 7 % S
% Thr: 7 69 0 0 0 0 0 0 7 0 0 7 0 7 63 % T
% Val: 0 0 0 7 0 0 0 0 0 7 0 0 0 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 7 0 0 7 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _